Methods and compositions for inhibiting cytomegalovirus...

Details Methods and compositions for inhibiting cytomegalovirus... Methods and compositions for inhibiting cytomegalovirus...

A - Human Necessities

61

K

A61K 31/66 (2006.01)

Patent

CA 2223874

Methods and compositions for use in inhibiting CMV replication in mammalian patients, wherein an effective amount of TPFA is administered to a patient in need of such treatment. TPFA is demonstrated to be at least as effective as PFA in inhibiting CMV viral replication, while having substantially improved bioavailability relative thereto.

Procédés et compositions servant à inhiber la réplication du cytomégalovirus (CMV) chez des mammifères, lesdits procédés consistant à leur administrer une quantité efficace de trisodium phosphonoformate. On a découvert que ce dernier est au moins aussi efficace que le phosphonoformate pour inhiber la réplication virale de CMV, tandis que sa biodisponibilité est sensiblement améliorée par rapport au phosphonoformate.

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