Methods and compositions for inhibition of angiogenesis

A - Human Necessities – 61 – K

Patent

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A61K 31/445 (2006.01) A61K 31/19 (2006.01) A61K 31/40 (2006.01) A61K 31/4035 (2006.01) A61K 31/44 (2006.01) A61K 31/454 (2006.01) A61K 31/535 (2006.01)

Patent

CA 2157288

The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, thalidomide and various related compounds such as thalidomide precursors analogs, metabolites and hydrolysis products have been shown to inhibit angiogenesis. Importantly, these compounds can be administered orally.

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