Methods and compositions for inhibition of metastasis

A - Human Necessities – 01 – N

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A01N 63/00 (2006.01) A61K 39/395 (2006.01) A61K 39/40 (2006.01) A61K 39/42 (2006.01) A61K 39/44 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 16/00 (2006.01) C12N 5/00 (2006.01) C12N 5/02 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/53 (2006.01) A01N 65/00 (2006.01)

Patent

CA 2559480

This invention generally relates to methods of producing an antibody phage population having affinity for a tumor cell target expressing a metastatic phenotype. The invention further relates to antibody compositions that specifically bind to a cell surface receptor on the metastatic cell.

La présente invention concerne des procédés pour produire une population de bactériophages d'anticorps qui présente une affinité pour une cellule tumorale cible exprimant un phénotype métastatique. La présente invention concerne également des compositions d'anticorps qui se lient de manière spécifique à un récepteur de surface cellulaire sur la cellule métastatique.

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