Methods and compositions for measuring wnt activation and...

Details Methods and compositions for measuring wnt activation and... Methods and compositions for measuring wnt activation and...

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2704648

The present application describes methods of regulating or modulating (e.g., antagonizing or inhibiting) Wnt sig-naling by administering Axin stabilizers. The application also describes methods of using Axin stabilizers described herein for the treatment, diagnosis, prevention, and/or amelioration of Wnt signaling-related disorders.

La présente invention porte sur des procédés de régulation ou de modulation (par exemple, d'antagonisation ou d'inhibition) de la signalisation Wnt par administration de stabilisants d'Axin. L'invention porte également sur des procédés d'utilisation de stabilisants d'Axin décrits ici pour le traitement, le diagnostic, la prévention et/ou l'amélioration de troubles se rapportant à la signalisation Wnt.

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