Methods and compositions for microencapsulation of antigens...

Details Methods and compositions for microencapsulation of antigens... Methods and compositions for microencapsulation of antigens...

A - Human Necessities

61

K

A61K 47/34 (2006.01) A61K 9/16 (2006.01) A61K 39/39 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2172507

Methods and compositions are provided for the encapsulation of adjuvants in PLGA microspheres for use as vaccines. Mixtures of microspheres are provided which release adjuvant at desired intervals to provide boosts with adjuvant.

L'invention concerne des procédés et des compositions s'utilisant dans la microencapsulation d'adjuvants dans des microsphères de poly(D-L-lactide-coglycolide) (PLGA) utilisées comme vaccins. L'invention concerne en outre des mélanges de microsphères qui libèrent lesdits adjuvants à intervalles voulus pour produire des effets de rappel.

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