Methods and compositions for microencapsulation of antigens...

A - Human Necessities – 61 – K

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A61K 47/34 (2006.01) A61K 9/16 (2006.01) A61K 9/56 (2006.01) A61K 39/00 (2006.01) A61K 39/21 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2172509

Methods and compositions are pro- vided for the encapsulation of antigens in PLGA microspheres for use as vaccines. Such microspheres can also contain adju- vants. Mixtures of microspheres are pro- vided which release antigen at desired in- tervals to provide boosts with antigens.

L'invention concerne les compositions et procédés de microencapsulation dans des microsphères de PLGA d'antigènes à utiliser comme vaccins. De telles microsphères peuvent également contenir des adjuvants. L'invention concerne également des microsphères capables de libérer l'antigène à intervalles spécifiques pour assurer une administration par vagues de l'antigène.

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