Methods and compositions for mineralizing and fluoridating...

C - Chemistry – Metallurgy – 01 – F

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C01F 11/22 (2006.01) A61K 6/033 (2006.01) A61K 8/24 (2006.01) A61K 33/06 (2006.01) A61K 33/24 (2006.01) A61K 33/42 (2006.01) A61Q 11/00 (2006.01) C01B 25/16 (2006.01) C01B 25/32 (2006.01) C01B 25/455 (2006.01) C01F 11/18 (2006.01)

Patent

CA 2121243

2121243 9404460 PCTABS00030 This invention involves new compositions and methods of use and delivery of amorphous calcium compounds such as: amorphous calcium phosphate (ACP), amorphous calcium phosphate fluoride (ACPF), amorphous calcium carbonate phosphate (ACCP), amorphous calcium carbonate phosphate fluoride (ACCPF), and amorphous calcium fluoride (ACF) for use in remineralizing and fluoridating teeth. These amorphous compounds or solutions which form the amorphous compounds, when applied either onto or into dental tissue prevent and/or repair dental weaknesses such as dental caries, exposed roots and dentin sensitivity. The compounds have the highest solubilities, fastest formation rates and fastest conversion rates (to apatite) among all the calcium phosphates under physiological conditions. Moreover, in the presence of fluoride the amorphous compound converts rapidly to fluoride containing apatite.

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