A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/28 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 38/44 (2006.01) A61K 38/45 (2006.01) A61K 39/395 (2006.01) A61K 45/06 (2006.01) C12N 15/85 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2628865
Methods are described for promoting or maintaining self-renewal of a stem cell expressing or expected to express p16INK4a by employing p16INK4a inhibitors. Methods are also described for increasing the amount of self-renewing stem cells in a non-infant subject, as well as for enhancing engraftment of a stem cell expressing p16INK4a. Additionally, methods are described for identifying p16INK4a inhibitors.
L'invention concerne des procédés permettant de favoriser ou de conserver l'auto-renouvellement d'une cellule souche exprimant ou censée exprimer p16INK4a, au moyen d'inhibiteurs de p16INK4a. L'invention concerne également des procédés permettant d'accroître la quantité de cellules souches à auto-renouvellement chez un sujet non-bébé, ainsi que d'améliorer la prise de greffe d'une cellule souche exprimant p16INK4a. De plus, l'invention concerne des procédés permettant d'identifier des inhibiteurs de p16INK4a.
Forkert Randolf
Janzen Viktor
Scadden David T.
Sharpless Norman E.
Gowling Lafleur Henderson Llp
The General Hospital Corporation
University Of North Carolina At Chapel Hill
LandOfFree
Methods and compositions for modulation of stem cell aging does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and compositions for modulation of stem cell aging, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions for modulation of stem cell aging will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1523773