Methods and compositions for opsonophagocytic assays

Details Methods and compositions for opsonophagocytic assays Methods and compositions for opsonophagocytic assays

G - Physics

01

N

G01N 33/564 (2006.01) G01N 33/533 (2006.01) G01N 33/554 (2006.01) G01N 33/569 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2643355

Methods and compositions comprising immunoassays for the detection of functional antibodies and the analysis of vaccine efficacy are described. In particular, the present invention provides opsonophagocytic assays. The assays are useful for the rapid and simultaneous detection of multiple different functional antibodies. In preferred embodiments, the assays include fluorescent labels of multiple colors and/or intensities.

Dans l'invention sont décrites des méthodes et des compositions associées à des essais immunologiques visant la détection d'anticorps fonctionnels et l'analyse de l'efficacité de vaccins. En particulier, la présente invention porte sur des essais d'opsonophagocytose. Les essais sont utiles pour déceler rapidement et simultanément plusieurs anticorps fonctionnels différents. Dans les modes de réalisation privilégiés, les essais font appel à des marqueurs fluorescents de différentes couleurs et/ou intensités.

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