Methods and compositions for oral delivery of fts

A - Human Necessities – 61 – K

Patent

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A61K 31/19 (2006.01) A61P 1/16 (2006.01) A61P 9/10 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2577310

Disclosed are oral dosage forms containing a Ras antagonist including FTS and structural analogs thereof, and at least one pharmaceutically acceptable excipient other than a cyclodextrin, and methods of orally administering same to treat diseases and disorders responsive to the Ras antagonists.

L'invention concerne des formes dosifées orales comprenant un antagoniste de Ras contenant un FTS et des analogues structurels de celui-ci, et au moins un excipient pharmaceutiquement acceptable autre qu'une cyclodextrine. L'invention concerne également des méthodes d'administration orale de ces formes dosifiées, mises en oeuvre dans le traitement des maladies et des troubles sensibles aux antagonistes de Ras.

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