C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A01K 67/027 (2006.01) A61K 31/513 (2006.01) A61K 31/593 (2006.01) A61K 31/7008 (2006.01) A61P 25/00 (2006.01) A61P 37/00 (2006.01) C12Q 1/00 (2006.01) C12Q 1/34 (2006.01) C12Q 1/48 (2006.01) C12Q 1/54 (2006.01)
Patent
CA 2595126
Contemplated compositions and methods are directed to prevent and/or treat various autoimmune diseases that are typically associated with glycan dysregulation, and especially autoimmune demyelinating diseases. Further especially contemplated aspects include animal models and systems for screening compounds to treat and/or prevent such diseases.
L'invention concerne des compositions et des procédés pour prévenir et/ou traiter diverses maladies auto-immunes typiquement associées à un dérèglement de glycane, notamment les maladies auto-immunes de démyélinisation. La présente invention porte également sur des modèles animaux et des systèmes pour cribler des composés destinés à prévenir et/ou traiter de telles maladies.
Demetriou Michael
Dennis James
Lau Ken Siu-Kwong
Mccarthy Tetrault Llp
Mount Sinai Hospital
The Regents Of The University Of California
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