Methods and compositions for promoting the maturation of...

A - Human Necessities – 61 – K

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A61K 38/19 (2006.01) A61K 31/00 (2006.01) A61K 31/415 (2006.01) A61K 38/20 (2006.01) A61K 39/39 (2006.01) A61P 31/12 (2006.01) A61P 33/00 (2006.01) A61P 35/00 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2425727

Disclosed is a method of promoting the maturation of monocytes comprising the administration of a reactive oxygen species (ROS) inhibitor or scavenger and at least one monocyte maturation-promoting agent. A composition for promoting the maturation of monocytes is likewise disclosed. The pharmaceutical composition includes a compound effective to promote the maturation of monocytes and a ROS inhibitor or scavenger combined in a pharmaceutically acceptable carrier.

L'invention concerne un procédé stimulant la maturation de monocytes qui consiste à administrer un inhibiteur ou un capteur d'espèces d'oxygène réactif et au moins un agent stimulant la maturation de monocytes. L'invention concerne également une composition stimulant la maturation de monocytes. Cette composition pharmaceutique comprend un composé efficace stimulant la maturation de monocytes et un inhibiteur ou un capteur d'espèces d'oxygène réactif associés dans un support acceptable sur le plan pharmaceutique.

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