Methods and compositions for rapid purification of...

C - Chemistry – Metallurgy – 07 – K

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C07K 1/22 (2006.01) C07K 14/00 (2006.01) C12N 5/00 (2006.01) C12Q 1/00 (2006.01) C07K 14/39 (2006.01) C12N 1/00 (2006.01) C12Q 1/37 (2006.01)

Patent

CA 2295322

Disclosed are methods for rapidly and efficiently purifying proteasomes using fusion proteins having homology to ubiquitin. Also disclosed are methods for assessing aberrant cell growth rates utilizing fusion proteins having homology to ubiquitin and a signal producing moiety.

L'invention porte sur des procédés visant à purifier rapidement et efficacement des protéasomes au moyen des protéines de fusion ayant une homologie avec l'ubiquitine, ainsi que sur des procédés permettant d'évaluer le taux de prolifération des cellules aberrantes au moyen des protéines de fusion ayant une homologie avec l'ubiquitine et d'une fraction générant un signal.

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