Methods and compositions for reducing toxicity associated...

Details Methods and compositions for reducing toxicity associated... Methods and compositions for reducing toxicity associated...

A - Human Necessities

61

K

A61K 31/42 (2006.01)

Patent

CA 2575119

The invention relates to methods and compositions useful in alleviating or reducing toxicity associated with leflunomide administration without reducing its bioactivity, e.g., without reducing its immunosuppressive activity, that is, utilizing a bioavailable pyrimidine compound to ameloriate the toxic effects caused by leflunomide compounds.

L'invention concerne des procédés et compositions utiles pour atténuer ou réduire la toxicité associée à l'administration du léflunomide sans réduire son activité biologique, c'est-à-dire sans réduire son activité immunosuppressive, à savoir en utilisant un composé de la pyrimidine biodisponible pour améliorer les effets toxiques provoqués par les composés du léflunomide.

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