Methods and compositions for regulating gut motility and...

C - Chemistry – Metallurgy – 07 – D

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C07D 493/10 (2006.01) A61K 31/335 (2006.01) A61K 31/353 (2006.01) A61P 1/10 (2006.01) A61P 1/12 (2006.01) A61P 3/04 (2006.01) C07D 493/00 (2006.01)

Patent

CA 2374358

Methods and compositions for regulating gut motility and food intake are described. Such compositions and methods may be used to treat obesity or to stimulate weight gain. Preferred compounds for controlling food intake are DON (4-deoxynivalenol) and derivatives thereof. Novel DON derivatives are also disclosed.

L'invention concerne des procédés et des compositions permettant de réguler le transit intestinal et la prise d'aliments. Ces compositions et ces procédés servent à traiter l'obésité ou à stimuler le gain de poids. On utilise de préférence le DON (4-désoxynivalénol) et ses dérivés comme composés de régulation de la prise d'aliments. L'invention concerne aussi de nouveaux dérivés de DON.

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