C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/00 (2006.01) A01K 67/027 (2006.01) A61K 35/30 (2006.01) A61K 49/00 (2006.01) A61P 25/28 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2366429
The present invention provides methods for identifying genes involved in memory consolidation, and for identifying agents which effect memory consolidation in a mammal. These methods preferably use (1) non-human mammals which have been manipulated to create at least partial disruption of fornix- mediated afferant signalling to the hippocampus, said disruption affecting memory consolidation or (2) non-lesioned mammals which have been subjected to a learning and memory test to provide a learned behavior in the mammal.
La présente invention concerne des méthodes permettant d'identifier des gènes intervenant dans la consolidation de la mémoire, et d'identifier des agents qui ont un effet sur la consolidation de la mémoire chez le mammifère.
Alberini Cristina M.
Bear Mark F.
Cooper Leon N.
Taubenfeld Stephen M.
Wiig Kjesten A.
Borden Ladner Gervais Llp
Brown University Research Foundation
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