Methods and compositions for screening for or modulating a...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 31/70 (2006.01) A61K 38/02 (2006.01) A61K 39/395 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2251344

Methods of screening for or treating cancer are disclosed. The screening methods are based on the detection of an antigen, or a nucleic acid molecule encoding the antigen, found by the present invention to be associated with the presence of cancer. Preferred embodiments of the methods include detection of the antigen based on immunological properties, physical properties, enzymatic properties and combinations thereof, or detection of a nucleic acid molecule encoding the antigen based on nucleic acid amplification.

Méthodes de dépistage ou de traitement du cancer. Les méthodes de dépistage se fondent sur la détection d'un antigène, ou d'une molécule d'acide nucléique codant l'antigène, cet antigène étant selon l'invention lié à la présence d'un cancer. Les modes de réalisation préférés sont notament la détection de l'antigène à partir de ses propriétés immunologiques, de ses propriétés physiques, de ses propriétés enzymatiques et de l'ensemble de celle-ci, ou la détection d'une molécule d'acide nucléique codant l'antigène à partir de l'amplification de l'acide nucléique.

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