Methods and compositions for selectin inhibition

Details Methods and compositions for selectin inhibition Methods and compositions for selectin inhibition

C - Chemistry, Metallurgy

07

D

C07D 215/20 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2544693

The present invention relates to the field of anti-inflammatory substances, and more particularly to novel compounds that act as antagonists of the mammalian adhesion proteins known as selectins. In some embodiments, methods for treating selectin mediated disorders are provided which include administration of compound of Formula: (I) wherein the constituent variables are defined herein.

L'invention concerne des substances anti-inflammatoires, et en particulier de nouveaux composés qui agissent comme des antagonistes des protéines d'adhésion mammifères connues sous le nom de sélectines. Dans certains modes de réalisation, l'invention concerne des méthodes de traitement des troubles médiés par la sélectine comprenant l'administration de composés de formule (I).

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