Methods and compositions for selectin inhibition

Details Methods and compositions for selectin inhibition Methods and compositions for selectin inhibition

C - Chemistry, Metallurgy

07

D

C07D 215/50 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2682183

The present teachings relate to compounds of formula I: wherein the constituent variables are defined herein. Compounds of the present teachings can act as antagonists of the mammalian adhesion proteins known as selectins. Methods for treating selectin mediated disorders are provided, which include administration of these compounds in a therapeutically effective amount.

La présente invention concerne des composés de formule I : dans laquelle les variables de constituant sont définies ici. Les composés de la présente invention peuvent agir comme antagonistes de protéines d'adhésion mammifères connues comme étant des sélectines. Des procédés de traitement de troubles véhiculés par la sélectine sont proposés, lesdits procédés comprennent l'administration de ces composés en une quantité efficace du point de vue thérapeutique.

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