Methods and compositions for selectin inhibition

C - Chemistry – Metallurgy – 07 – D

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C07D 215/20 (2006.01) A61K 31/47 (2006.01) A61K 31/475 (2006.01) C07D 401/06 (2006.01) C07D 409/06 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2543765

The present invention relates to the field of anti-inflammatory substances, and more particularly to novel compounds that act as antagonists of the mammalian adhesion proteins known as selectins. In some embodiments, methods for treating selectin mediated disorders are provided which include administration of compound of Formula ( I ): wherein the constituent variables are defined herein.

La présente invention concerne le domaine des substances anti-inflammatoires et plus particulièrement de nouveaux composés qui fonctionnent comme des antagonistes des protéines d'adhérence connues sous le nom de sélectines. Dans certains modes de réalisation, l'invention porte sur des procédés destinés à traiter des troubles à médiation par sélectine, qui comprennent l'administration du composé correspondant yant la formule I, les parties constitutives étant définies dans le descriptif.

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