Methods and compositions for slowing aging

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 471/04 (2006.01) A61K 31/437 (2006.01)

Patent

CA 2548487

The present invention provides a pharmacological agent based on derivatives of hydrogenated pyrido (4,3-b) indoles and uses thereof. Specifically, the invention provides a geroprotector in the series of hydrogenated pyrido (4,3- b) indoles (several derivatives), which can be used for slowing aging, prolonging lifespan of an individual or cells in an individual, and/or improving quality of life of an individual developing or having a risk of developing age-associated manifestations and/or pathologies.

L'invention concerne un agent pharmaceutique à base de dérivés de pyrido (4,3-b) indoles hydrogénés, ainsi que les utilisations de celui-ci. De manière plus spécifique, l'invention concerne un protecteur contre le vieillissement de la série des pyrido (4,3-b) indoles hydrogénés (différents dérivés), qui peut être utilisé pour ralentir le vieillissement, prolonger la durée de vie d'un individu ou de cellules d'un individu, et/ou pour améliorer la qualité de vie d'un individu présentant ou risquant de voir apparaître des manifestations et/ou des pathologies liées à l'âge.

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