C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/53 (2006.01) A23D 9/00 (2006.01) A23K 1/16 (2006.01) A23L 1/29 (2006.01) A23L 1/30 (2006.01) A61K 31/20 (2006.01) C11B 1/00 (2006.01) C12N 1/19 (2006.01) C12N 5/10 (2006.01) C12N 9/02 (2006.01) C12N 15/81 (2006.01) C12N 15/82 (2006.01) C12P 7/64 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2285968
The present invention relates to fatty acid desaturases able to catalyze the conversion of oleic acid to linoleic acid, linoleic acid to .gamma.-linolenic acid, or of alpha-linolenic acid to stearidonic acid. Nucleic acid sequences encoding desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising a desaturase gene, and recombinant host microorganism or animal expressing increased levels of a desaturase are described. Methods for desaturating a fatty acid and for producing a desaturated fatty acid by expressing increased levels of a desaturase are disclosed. Fatty acids, and oils containing them, which have been desaturated by a desaturase produced by recombinant host microorganisms or animals are provided. Pharmaceutical compositions, infant formulas or dietary supplements containing fatty acids which have been desaturated by a desaturase produced by a recombinant host microorganism or animal also are described.
La présente invention concerne des désaturases d'acides gras capables de catalyser la conversion d'acide oléique en acide linoléique, d'acide linoléique en acide .gamma.-linoléique, ou d'acide .alpha.-linoléique en acide staridonique. L'invention concerne également des séquences d'acide nucléique codant les désaturases, des séquences d'acide nucléique qui s'hybrident à ces premières séquences, des constructions d'ADN comprenant un gène désaturase, et un micro-organisme ou un animal hôte recombinant exprimant des niveaux accrus d'une désaturase. L'invention concerne en outre des procédés de désaturation d'un acide gras et de production d'un acide gras désaturé par expression de niveaux accrus d'une désaturase. L'invention concerne par ailleurs des acides gras, et des huiles contenant de tels acides, qui ont été désaturés par une désaturase produite par des micro-organismes ou des animaux hôtes recombinants. L'invention concerne enfin des compositions pharmaceutiques, des formules infantiles ou des compléments alimentaires contenant des acides gras qui ont été désaturés par une désaturase produite par un micro-organisme ou un animal hôte recombinant.
Chaudhary Sunita
Huang Yung-Sheng
Knutzon Deborah
Leonard Amanda Eun-Yeong
Mukerji Pradip
Abbott Laboratories
Calgene Llc
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
LandOfFree
Methods and compositions for synthesis of long chain... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and compositions for synthesis of long chain..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions for synthesis of long chain... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1587868