C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 21/08 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 49/08 (2006.01) A61K 51/10 (2006.01) C07K 16/22 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2131528
The present invention relates generally to methods and compositions for targeting the vasculature of solid tumors using im- munologically-based reagents. In particular aspects, antibodies carrying diagnostic or therapeutic agents are targeted to the vas- culature of solid tumor masses through recognition of tumor vasculature- associated antigens, or through the specific induction of endothelial cell surface antigens on vascular endothelial cells in solid tumors.
Burrows Francis J.
Thorpe Philip E.
Imperial Cancer Research Technology
R. William Wray & Associates
The Board Of Regents Of The University Of Texas
The Board Of Regents Of The University Of Texas System
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