Methods and compositions for targeting the vasculature of...

Details Methods and compositions for targeting the vasculature of... Methods and compositions for targeting the vasculature of...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 45/00 (2006.01) A61K 47/42 (2006.01) A61K 49/16 (2006.01) A61K 51/10 (2006.01) A61P 35/00 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2452130

The present invention relates generally to methods and compositions for targeting the vasculature of solid tumors using immunologically-based reagents. In particular aspects, antibodies carrying diagnostic or therapeutic agents are targeted to the vasculature of solid tumor masses through recognition of tumor vasculature-associated antigens, or through the specific induction of endothelial cell surface antigens on vascular endothelial cells in solid tumors.

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