C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2655269
The invention relates to methods and kits for the amplification, detection and quantification of a nucleic acid from a sample. The methods of the invention may be used in a wide range of applications, including, but not limited to, the detection and quantification of fetal nucleic acid from maternal plasma, the detection and quantification of circulating nucleic acids from neoplasms (malignant or non-malignant), accurate pooling analysis for low frequency alleles, or any other application requiring sensitive quantitative analysis of nucleic acids.
La présente invention concerne des procédés et des trousses destinés à l'amplification, la détection et la quantification d'un acide nucléique issu d'un échantillon. Les procédés de l'invention peuvent être utilisés pour une large gamme d'applications, incluant, mais sans s'y limiter, la détection et la quantification d'acide nucléique fAEtal provenant du plasma maternel, la détection et la quantification d'acides nucléiques circulants originaires de néoplasmes (malins ou bénins), l'analyse de regroupement précise d'allèles de faible fréquence, ou tout autre application requérant une analyse quantitative sensible d'acides nucléiques.
Sequenom Inc.
Smart & Biggar
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