C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 31/7088 (2006.01) A61K 31/7105 (2006.01) A61P 35/00 (2006.01) C40B 30/04 (2006.01) C40B 40/06 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01) C07H 21/02 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01)
Patent
CA 2702241
Methods and compositions for the diagnosis, prognosis and/or treatment of esophageal adenocarcinoma and Bar-rett's esophagus associated adenocarcinoma are disclosed, along with more markers where a difference is indicative of esophageal adenocarcinoma and squamous cell carcinoma, and/or Barrett's esophagus associated adenocarcinomas or a predisposition thereto. The invention also provides methods and compositions of identifying anti- cancer agents therefor.
La présente invention concerne des procédés et des compositions destinés au diagnostic, au pronostic et/ou au traitement de l'adénocarcinome de l'sophage et de l'sophage de Barrett associé à l'adénocarcinome. L'invention concerne également plusieurs marqueurs où une différence indique un adénocarcinome de l'sophage et un carcinome des cellules squameuses, et/ou un sophage de Barrett associé à un adénocarcinome ou une prédisposition à celui-ci. L'invention concerne également des procédés et des compositions d'identification d'agents anticancéreux destinés à ces utilisations.
Croce Carlo M.
Harris Curtis C.
Mathe Ewy A.
Ridout & Maybee Llp
The Government Of The United States Of America As Represented By
The Ohio State University Research Foundation
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