Methods and compositions for the prevention or treatment of...

Details Methods and compositions for the prevention or treatment of... Methods and compositions for the prevention or treatment of...

A - Human Necessities

61

K

A61K 38/44 (2006.01) A61K 9/06 (2006.01) A61K 9/12 (2006.01) A61P 15/00 (2006.01) A61P 31/04 (2006.01) A61P 31/10 (2006.01)

Patent

CA 2158576

Methods and compositions for the prophylaxis and/or treatment of sexually transmitted diseases (STDs) are disclosed, in which amounts of a haloperoxidase, such as myeloperoxidase or eosinophil peroxidase, and a semen substrate-specific oxidase are administered to a human or animal subject in the environment of sexually transmitted fluids. In the presence of semen, the semen substrate-specific oxidase catalyzes the production of hydrogen peroxide, which in turn is utilized by the haloperoxidase to selectively inhibit pathogenic microbes present in the sexually transmitted fluids. At high concentration levels, the compositions additionally exhibit spermicidal properties.

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