Methods and compositions for the promotion of hair growth...

A - Human Necessities – 61 – K

Patent

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A61K 8/64 (2006.01) A61Q 7/00 (2006.01)

Patent

CA 2473996

Disclosed herein are methods and compositions suitable for the promotion of hair growth on humans and other animals. Disclosed embodiments include compositions comprising actin-binding peptides. In some embodiments, the actin- binding peptides comprise fragments of thymosin .beta.4. In other embodiments, the disclosure provides compositions comprising fragments of thymosin .beta.4 and/or other actin-binding peptides that are suitable for the treatment of alopecia and other conditions associated with hair loss. In still further embodiments, the disclosure provides compositions comprising the sequence of approximately six or seven amino acids of the thymosin .beta. 4 sequence that bind actin.

L'invention concerne des procédés et des compositions favorisant la pousse de cheveux chez des humains et d'autres animaux. Selon des modes de réalisation, l'invention concerne des compositions renfermant des peptides de liaison d'actine. Selon certains modes de réalisation, les peptides de liaison d'actine renferment des fragments de thymosine ?¿4?. Selon d'autres modes de réalisation, l'invention concerne des compositions renfermant des fragments de thymosine ?¿4 ?et/ou d'autres peptides de liaison d'actine se prêtant au traitement de l'alopécie et d'autres pathologies associées à la perte de cheveux. Selon des modes de réalisation supplémentaires, l'invention concerne des compositions comprenant la séquence d'environ six ou sept acides aminés de la séquence de thymosine ?¿ 4 ?se liant avec l'actine.

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