A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/10 (2006.01)
Patent
CA 2619650
The present invention features compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, Inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo- obstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation (post-operative ileus), and constipation associated with neuropathic disorders as well as other conditions and disorders using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
L'invention concerne des compositions et des méthodes associées destinées à traiter le syndrome du côlon irritable et d'autres troubles et affections gastro-intestinaux (p. ex. troubles de la motilité gastro-intestinale, troubles gastro-intestinaux fonctionnels, reflux gastro-oesophagien pathologique, reflux duodénogastrique, maladie de Crohn, rectocolite hémorragique, affection abdominale inflammatoire, brûlures d'estomac fonctionnelles, dyspepsie (y compris la dyspepsie fonctionnelle ou dyspepsie non ulcéreuse), gastroparésie, pseudo-obstruction intestinale chronique (ou pseudo-obstruction du côlon)), les troubles et affections associés à la constipation, p. ex. constipation associée à l'utilisation d'antidouleurs opiacés, constipation post-chirurgicale (occlusion intestinale post-opératoire), constipation associée à des troubles neuropathiques, ainsi que d'autres affections et troubles, lesdites compositions et méthodes utilisant des peptides et d'autres agents activant le récepteur de la guanylate cyclase C (GC-C).
Currie Mark G.
Fretzen Angelika
Kurtz Caroline
Mahajan-Miklos Shalina
Milne G. Todd
Ironwood Pharmaceuticals Inc.
Microbia Inc.
Smart & Biggar
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