Methods and compositions for the treatment of...

A - Human Necessities – 61 – K

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A61K 31/708 (2006.01) A61K 31/215 (2006.01) A61P 1/00 (2006.01) C07H 19/20 (2006.01)

Patent

CA 2630241

The present invention features compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, Inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis employing. The methods and compositions employ guanosine 3', 5'- cyclic monophosphate pharmaceutically acceptable salt thereof.

La présente invention concerne des compositions et des procédés liés au traitement de l'IBS et autres désordres et conditions gastro-intestinaux (p. ex. des désordres de motilité gastrointestinale, des désordres gastrointestinaux fonctionnels, le reflux gastro-oesophagien (GERD), le reflux duodénogastrique, la maladie de Crohn, la colite ulcéreuse, l'affection abdominale inflammatoire, les brûlures d~estomac, la dyspepsie (y compris la dyspepsie fonctionnelle ou la dyspepsie non ulcéreuse), employant la gastroparésie. Les procédés et compositions emploient la guanosine 3' et un sel dérivé pharmaceutiquement acceptable 5'-cyclique monophosphate.

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