A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/00 (2006.01)
Patent
CA 2514507
The present invention features compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), Crohn's disease, ulcerative colitis, Inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
L'invention concerne des compositions et des procédés associés conçus pour traiter le syndrome du côlon irritable (IBS) et autres troubles et états gastro-intestinaux (tels que troubles de la motilité gastro-intestinale, troubles gastro-intestinaux fonctionnels, reflux gastrooesophagien pathologique (GERD), maladie de Crohn, recto-colite ulcéro-hémorragique, maladie intestinale inflammatoire, aigreurs, dyspepsie (y compris la dyspepsie fonctionnelle ou la dyspepsie non ulcéreuse), gastroparésie, pseudo-obstruction intestinale chronique (pseudo-obstruction du côlon), et troubles et états associés à la constipation, tels que constipation liée à l'utilisation d'anti-douleurs opiacés, constipation post-opératoire, et constipation liée à des troubles neuropathiques ainsi que d'autres états et troubles utilisant des peptides et autres agents qui activent le récepteur guanylate cyclase C (GC-C).
Currie Mark G.
Mahajan-Miklos Shalina
Milne G. Todd
Norman Thea
Ironwood Pharmaceuticals Inc.
Microbia Inc.
Smart & Biggar
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