Methods and compositions for the treatment of...

Details Methods and compositions for the treatment of... Methods and compositions for the treatment of...

A - Human Necessities

61

K

A61K 31/402 (2006.01) A61K 31/196 (2006.01) A61K 31/4425 (2006.01) A61K 31/635 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2625362

The present invention relates to methods and compositions for treating neuropathic pain and neuropsychiatric disorders by administering agents that are effective in reducing the effective amount, inactivating, and/or inhibiting the activity of a Na+-K+-2Cl- (NKCC) cotransporter. In certain embodiments, the Na+-K+-2Cl- co-transporter is NKCC1.

La présente invention concerne des procédés et des compositions pour traiter une douleur neuropathique et des troubles neuropsychiatriques, comprenant l'administration d'agents qui permettent de réduire la quantité efficace, d'inactiver et/ou d'inhiber l'activité d'un co-transporteur Na+-K+-2Cl- (NKCC). Dans certains modes de réalisation, le co-transporteur Na+-K+-2Cl- est NKCC1.

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