Methods and compositions for the treatment of anxiety disorders

A - Human Necessities – 61 – K

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A61K 31/195 (2006.01) A61K 31/18 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2604446

The present invention relates to methods and compositions for treating neuropathic pain and neuropsychiatric disorders by administering agents that are effective in reducing the effective amount, inactivating, and/or inhibiting the activity of a Na+-K+-2Cl- (NKCC) cotransporter. In certain embodiments, the Na+-K+-2Cl- co-transporter is NKCCl.

La présente invention concerne des méthodes et des compositions destinées à traiter une douleur neuropathique et des troubles neuropsychiatriques par administration d'agents efficaces pour réduire la dose efficace d'un co-transporteur Na+-K+-2Cl- (NKCC), pour inactiver ce co-transporteur et/ou pour en inhiber l'activité. Dans certains modes de réalisation, le co-transporteur Na+-K+-2Cl- est NKCCl.

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