Methods and compositions for the treatment of ischemic...

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61K 9/127 (2006.01) A61K 31/4365 (2006.01) A61K 31/60 (2006.01) A61K 31/727 (2006.01) A61K 38/49 (2006.01)

Patent

CA 2485989

The invention provides methods and compositions for treating or preventing ischemic reperfusion injury. The methods of the instant invention comprise the administration of compositions comprising apolipoproteins, lecithin cholesterol acyltransferase or paraoxo nase to treat, reduce or prevent ischemic reperfusion injury.

La présente invention se rapporte à des méthodes et à des compositions permettant de traiter ou de prévenir une lésion de reperfusion ischémique. Les méthodes de la présente invention consistent à administrer des compositions comportant des apolipoprotéines, une lecithine-cholestérol acyltransférase ou une paraoxonase, de manière à traiter, à réduire ou à prévenir les lésions de reperfusion ischémique.

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