Methods and compositions for the treatment of psychotic and...

Details Methods and compositions for the treatment of psychotic and... Methods and compositions for the treatment of psychotic and...

A - Human Necessities

61

K

A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 45/06 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2363942

The invention relates to novel methods using, and pharmaceutical compositions comprising, ziprasidone metabolites, preferrably its sulfone and sulfoxide. The methods and compositions of the invention are suitable for the treatment of psychotic and related disorders and Parkinson's disease, migraines, porphyria, epilepsy. The invention further encompasses methods of preparing ziprasidone sulfoxide and ziprasidone sulfone.

L'invention concerne de nouvelles méthodes dans lesquelles on utilise des métabolites de ziprasidone, ainsi que des compositions pharmaceutiques comprenant ces mêmes métabolites. Les méthodes et les compositions de la présente invention conviennent pour le traitement de troubles neuroleptiques et associés. L'invention porte également sur des méthodes de préparation de sulfoxyde de ziprasidone et de sulfone de ziprasidone.

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