Methods and compositions for the use of stromal cells to...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/02 (2006.01) C12N 5/0735 (2010.01) C12N 5/074 (2010.01) C12N 5/077 (2010.01) A61K 35/12 (2006.01)

Patent

CA 2466880

The invention provides cells, compositions and methods based on the use of stromal cells to support the proliferation of undifferentiated embryonic or adult stem cells in vitro. The stem cells produced in the method are useful in providing a source of uncommitted or differentiated and functional cells for research, transplantation and development of tissue engineered products for the treatment of human diseases and traumatic tissue injury repair in any tissue or organ site within the body.

La présente invention concerne des cellules, des compositions et des méthodes qui sont fondées sur l'utilisation de cellules stromales pour supporter, in vitro, la prolifération de cellules souches embryonnaires et adultes indifférenciées. Les cellules souches produites selon cette méthode sont utiles en tant que source de cellules fonctionnelles, disponibles ou différenciées pour la recherche, la transplantation et la création de produits tissulaires fabriqués/modifiés par génie génétique destinés au traitement des maladies humaines et à la réparation des blessures tissulaires traumatiques de n'importe quel tissu ou organe interne du corps.

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