Methods and compositions for tissue regeneration

Details Methods and compositions for tissue regeneration Methods and compositions for tissue regeneration

A - Human Necessities

61

L

A61L 15/40 (2006.01) C12N 5/071 (2010.01) A61K 35/00 (2006.01) A61K 35/12 (2006.01) A61L 26/00 (2006.01) A61L 27/38 (2006.01)

Patent

CA 2426107

The present invention provides the use and composition of matter of angiogenic or other growth factors expressed by combining various types and stages of differentiation of allogeneic human cell strains or lines in unencapsulated pastes (mixed with or applied to extracellular matrix material or synthetic biocompatible substances) to be temporarily applied to wounds or defects in the skin or other tissues for the restoration of blood supplying connective tissue to enable organ-specific cells to reestablish organ integrity as well as to inhibit excessive scar formation.

Cette invention a trait à l'utilisation, ainsi qu'à la composition correspondante, de facteurs angiogéniques ou d'autres facteurs de croissance exprimés par la combinaison de différents types et stades de différenciation de souches ou de lignées cellulaires allogènes humaines dans des pâtes non encapsulées (mélangées à une substance de matrice extracellulaire ou de substances synthétiques biocompatibles ou déposée sur ces substances) à appliquer un temps donné sur des lésions ou sur des anomalies de la peau ou d'autres tissus aux fins de la restauration du tissu conjonctif d'alimentation sanguine et ce, afin de permettre à des cellules spécifiques d'un organe d'en restaurer l'intégrité ainsi que d'empêcher une formation cicatricielle excessive.

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