A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/195 (2006.01) A61K 31/66 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 45/06 (2006.01) A61P 25/28 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2441469
The present invention provides methods for reducing the efflux of cholesterol and/or secreted A.beta. in the brain, as well as methods for treating Alzheimer's disease, by inhibit the expression and/or activity of LXR and/or ABCA1. Compositions comprising agents for performing the methods also are provided.
Deng Amy
Fitzgerald Michael
Fukumoto Hiroaki
Irizarry Michael C.
Rebeck G. William
Smart & Biggar
The General Hospital Corporation
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