Methods and compositions for treating and diagnosing tumors...

Details Methods and compositions for treating and diagnosing tumors... Methods and compositions for treating and diagnosing tumors...

A - Human Necessities

61

K

A61K 31/7076 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 51/00 (2006.01) A61K 51/04 (2006.01) A61M 36/14 (2006.01)

Patent

CA 2271203

Methods of treating and/or imaging tumors utilize A1 adenosine-receptor activated cells (such as monocytes and macrophages) are described. Activated cells may be administered systemically or locally, and may be radiolabelled to provide imaging and diagnostic functions. Macrophages resident in tissues may be primed and activated for use in treating and imaging tumors.

L'invention concerne des procédés de traitement et/ou d'imagerie de tumeurs dans lesquels on utilise des cellules activées du récepteur de l'adénosine A¿1? (telles que des monocytes et des macrophages). On peut administrer ces cellules activées par voie systémique ou locale, et on peut les radiomarquer afin d'obtenir des fonctions d'imagerie et de diagnostic. On peut sensibiliser et activer des macrophages résidant dans des tissus, afin de les utiliser dans le traitement et l'imagerie de tumeurs.

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