Methods and compositions for treating and preventing...

Details Methods and compositions for treating and preventing... Methods and compositions for treating and preventing...

A - Human Necessities

61

K

A61K 39/385 (2006.01) A61K 38/19 (2006.01) A61K 38/20 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2519114

Methods of treating eosinophilia by down regulating eotaxin and at least one other Th-2 related cytokine are dislosed as are multivalent immunogenic compositions that generate an active immune response in a subjet comprising autoantibodies to eotaxin-1, eotaxin-2, IL-4, IL-5, IL-9, and IL-13 and treatment methods using such compositions.

L'invention concerne des méthodes de traitement de l'éosinophilie par régulation restrictive de l'éotaxine et d'au moins une autre cytokine apparentée au type 2-Th ainsi que des compositions immunogènes polyvalentes qui génèrent une réponse immunitaire active chez un sujet possédant des anticorps dirigés contre l'éotaxine 1, l'éotaxine 2, l'éotaxine 3, IL-4, IL-5, IL-9 et IL-13. L'invention porte également sur des méthodes de traitement dans lesquelles lesdites compositions sont utilisées.

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