A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/496 (2006.01)
Patent
CA 2649720
Pharmaceutical compositions comprising the 2S,4R ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates are useful to increase cardiolipin synthesis and for the treatment of Barth Syndrome, diabetic myopathy, cardiomyopathy associated with aging, mitochondrial disease, and other conditions and disorders where cardiolipin deficiency plays a causative or symptomatic role.
La présente invention concerne des compositions pharmaceutiques comprenant l'énantiomère 2S,4R du kétoconazole ou ses sels, ses hydrates ou ses solvates pharmaceutiquement acceptables, lesdites compositions pharmaceutiques étant utilisables pour augmenter la synthèse du cardiolipide et pour traiter le syndrome de Barth, la myopathie diabétique, la cardiomyopathie associée au vieillissement, la maladie mitochondriale et d'autres affections et troubles dans lesquels une insuffisance en cardiolipide joue un rôle causatif ou symptomatique.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Cortendo Invest Ab
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