Methods and compositions for treating cancer

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 211/00 (2006.01) C07D 209/04 (2006.01) C07J 1/00 (2006.01)

Patent

CA 2601038

The invention provides compounds and methods for treating cancer. Exemplary compounds are multi-functional compounds with two different moieties connected by a linker. Compounds of the invention can activate one or more pathways that results in the inhibition of cell growth. The invention includes cytostatic and cytotoxic compounds. Methods and compositions of the invention are particularly useful for treating cancer cells that are resistanct to other chemotherapeutic drugs.

La présente invention a trait à des composés et des procédés pour le traitement du cancer. Des composés représentatifs sont des composés multifonctions avec deux différents groupes fonctionnels liés par un lieur. Des composés de l'invention peuvent assurer l'activation d'une ou de plusieurs voies entraînant l'inhibition de la croissance cellulaire. L'invention a également trait à des composés cytostatiques et cytotoxiques. Les procédés et compositions de l'invention sont particulièrement utiles pour le traitement des cellules cancéreuses qui sont résistantes aux autres médicaments chimiothérapeutiques.

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