Methods and compositions for treating cancer

A - Human Necessities – 61 – K

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Details

A61K 9/20 (2006.01) A61K 31/353 (2006.01) C07D 311/62 (2006.01) C07D 311/78 (2006.01)

Patent

CA 2554140

This invention relates to compositions, and methods of use thereof, containing polyphenols such as procyanidins and derivatives thereof, for treating certain tumors, and more generally to inducing dephosphorylation of a hyperphosphorylated cell cycle regulatory protein in a tumor cell in which hyperphosphorylation of said protein contributed to cell transformation.

Cette invention porte sur des compositions et sur leurs procédés d'utilisation, ces compositions contenant des polyphénols tels que des procyanidines et leurs dérivés, et s'utilisant dans le traitement de certaines tumeurs et, plus généralement, pour induire la déphosphorylation d'une protéine régulatrice du cycle cellulaire hyperphosphorylé dans une cellule tumorale dans laquelle l'hyperphosphorylation de cette protéine a contribué à la transformation des cellules.

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