Methods and compositions for treating cancers

A - Human Necessities – 61 – K

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A61K 45/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2699988

This invention provides a combination of antagonists of the hedgehog signaling pathway with a BCR-ABL inhibitor. The combination of the present invention may be used for treating cancers known to be associated with protein tyrosine kinases such as, for example, Src, BCR-ABL and c-kit.

Cette invention propose une combinaison d'antagonistes de la voie de signalisation du hérisson avec un inhibiteur de BCR-ABL. La combinaison de la présente invention peut être utilisée pour traiter des cancers connus comme étant associés à des protéine tyrosine kinases, telles que, par exemple Src, BCR-ABL et c-kit.

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