C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/869 (2006.01) A61K 38/45 (2006.01) A61K 39/12 (2006.01) A61K 48/00 (2006.01) C12N 7/01 (2006.01) C12N 15/34 (2006.01)
Patent
CA 2306355
The present invention relates to methods and compositions for treating human cells. In particular, the invention relates to the use of an Equine herpes virus type-4 (EHV4) thymidine kinase polypeptide or a nucleic acid coding therefor for the manufacture of a composition to render human cells sensitive to a nucleoside analog in vitro, ex vivo or in vivo. The invention can be used in experimental, biological, screening or therapeutical applications.
Klatzmann David
Loubiere Laurence
Robic
Universite Pierre Et Marie Curie (paris Vi)
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