Methods and compositions for treating hyperalgesia

Details Methods and compositions for treating hyperalgesia Methods and compositions for treating hyperalgesia

A - Human Necessities

61

K

A61K 31/197 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2643031

This invention provides compounds which specifically inhibit TRPA1 but not other members of the thermoTRP ion channel family. Also provided in the invention are methods of using TRPA1-specific inhibitors to treat or alleviate pains mediated by noxious mechanosensation.

La présente invention concerne des composés qui inhibent spécifiquement TRPA1 mais pas d'autres membres de la famille du canal ionique thermoTRP. Elle concerne aussi des méthodes utilisant des inhibiteurs TRPA1 spécifiques pour traiter ou soulager des douleurs provenant d'une sensibilité mécanique nocive.

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