Methods and compositions for treating lupus

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2761885

The invention provides methods of treating lupus in a patient with an anti-CD52 antibody. Also includes are methods of increasing infiltration of regulatory T cells to affected sides of the patient's body, methods of reducing urine protein and/or albumin levels and methods of depleting lymphocytes to alleviate lupus symptoms.

L'invention porte sur des procédés de traitement d'un lupus chez un patient avec un anticorps anti-CD52. L'invention comprend également des procédés d'augmentation de l'infiltration des lymphocytes T régulateurs vers des sites affectés du corps du patient, sur des procédés de réduction des taux de protéine urinaires et/ou d'albumine et sur des procédés d'appauvrissement en lymphocytes pour soulager les symptômes du lupus.

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