Methods and compositions for treating mammalian nerve tissue...

A - Human Necessities – 61 – K

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A61K 31/765 (2006.01) A61F 13/00 (2006.01) A61K 31/74 (2006.01)

Patent

CA 2445612

To achieve, an in vivo repair of injured mammalian nerve tissue, an effective amount of a biomembrane fusion agent is administered to the injured nerve tissue. The application of the biomembrane fusion agent may be performed by directly contacting the agent with the nerve tissue at the site of the injury. Alternatively, the biomembrane fusion agent is delivered to the site of the injury through the blood supply after administration of the biomembrane fusion agent to the patient. The administration is preferably by parenteral administration including intravascular, intramuscular, subcutaneous, or intraperitoneal injection of an effective quantity of the biomembrane fusion agent so that an effective amount is delivered to the site of the nerve tissue injury.

Afin de réparer in vivo du tissu nerveux mammaire endommagé, une quantité efficace d'agent de fusion de membrane biologique est administré au tissu nerveux endommagé. L'application de l'agent de fusion de membrane biologique peut être réalisée par contact direct dudit agent avec le tissu nerveux à l'endroit de l'endommagement. Mais il peut également être amené sur le site de l'endommagement par l'apport sanguin après administration de l'agent de fusion de membrane biologique au patient. De préférence parentérale, l'administration est réalisée par injection intravasculaire, intramusculaire, sous-cutanée ou intrapéritonéale d'une quantité efficace d'agent de fusion de membrane biologique, de manière à ce qu'une quantité suffisante soit fournie à l'endroit de l'endommagement du tissu nerveux.

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