Methods and compositions for treating pain

Details Methods and compositions for treating pain Methods and compositions for treating pain

A - Human Necessities

61

K

A61K 31/353 (2006.01) A61K 31/197 (2006.01) A61K 31/485 (2006.01) A61P 39/00 (2006.01)

Patent

CA 2587406

Methods and compositions are described for the modulation of central nervous system and/or fetal effects of substances. Methods and compositions are described for the modulation of efflux transporter activity to increase the efflux of drugs and other compounds out of a physiological compartment and into an external environment. In particular, the methods and compositions disclosed herein provide for the increase of efflux transporter activity at blood-brain, blood-CSF and placental-maternal barriers to increase the efflux of drugs and other compounds from physiological compartments, including central nervous system and fetal compartments.

Procédés et compositions pour la modulation du système nerveux central et/ou d'effets foetaux de substances. Procédés et compositions pour la modulation de l'activité de transport d'écoulements afin d'augmenter l'écoulement de médicaments et d'autres composés sortant d'un compartiment physiologique et entrant dans un environnement externe. Plus particulièrement, les procédés et compositions assurent l'augmentation de l'activité de transport d'écoulement au niveau des barrières sang-cerveau, sang-CSF et placenta-mère de manière à augmenter l'écoulement de médicaments et d'autres composés à partir de compartiments physiologiques, y compris le système nerveux central et les compartiments foetaux.

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