Methods and compositions for treating prostate cancer

Details Methods and compositions for treating prostate cancer Methods and compositions for treating prostate cancer

A - Human Necessities

61

K

A61K 31/497 (2006.01)

Patent

CA 2637000

Pharmaceutical compositions comprising the 2S,4R ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R,4S ketoconazole enantiomer are useful to reduce testosterone synthesis and for the treatment of prostate cancer, benign prostatic hyperplasia, seborrhea, hirsutism, alopecia, polycystic ovary syndrome, and other diseases and conditions, including but not limited to systemic hyperandrogenism.

L'invention porte sur des préparations pharmaceutiques comprenant l'énantiomère du kétoconazole 2S,4R énantiomère ou ses sels, hydrates et solvates pharmacocompatibles, sensiblement exempts de l'énantiomère du kétoconazole 2R,4S, et s'avérant utiles pour réduire la synthèse du testostérone, et traiter le cancer de la prostate, l'hyperplasie bénigne de la prostate, la séborrhée, l'hirsutisme, l'alopécie, le syndrome des ovaires polycystiques, et d'autres maladies ou troubles dont non limitativement l'hyperandrogénisme systémique.

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